2025 Nfl Schedule 49ers 2025. The san francisco 49ers have another opportunity on their 2025 schedule to play a game overseas. 2026 san francisco 49ers schedule;

2025 nfl playoff schedule, bracket, scores: Here is who the san francisco 49ers will play at home and on the road during the 2025 nfl season after securing last place in the nfc west in 2024.